Holding(s) in Company
City of Hope has acquired a significant stake in Thalia Therapeutics PLC, now holding 10.6% of the company's voting rights, which equates to 188,779,668 shares. This acquisition represents a substantial increase from their previous holding of 0.0%. The notification was made on July 20, 2026, reflecting the date the threshold was crossed.
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Non-UK issuer
- Reason for the notification (please mark the appropriate box or boxes with an "X")
| An acquisition or disposal of voting rights | X |
An acquisition or disposal of financial instruments
An event changing the breakdown of voting rights
Other (please specify) iii :
Details of person subject to the notification obligation iv
| Name | City of Hope |
| City and country of registered office (if applicable) | Duarte, California, United States of America |
Full name of shareholder(s) (if different from 3.) v
Name
City and country of registered office (if applicable)
| 5. Date on which the threshold was crossed or reached vi : | 20 July 2026 |
| 6. Date on which issuer notified (DD/MM/YYYY): | 20 July 2026 |
- Total positions of person(s) subject to the notification obligation
| Resulting situation on the date on which threshold was crossed or reached | 10.6% | 10.6% | 188,779,668 |
| Position of previous notification (if applicable) | 0.0% | 0.0% | |
| A: Voting rights attached to shares | |||
| Class/type of shares ISIN code (if possible) | Number of voting rights ix | % of voting rights | |
| Direct (DTR5.1) | Indirect (DTR5.2.1) | Direct (DTR5.1) | Indirect (DTR5.2.1) |
| Ordinary shares of 0.4p (GB00BYW8QM32) | 188,779,668 | 10.6% | |
| SUBTOTAL 8. A | 188,779,668 | 10.6% | |
B 1: Financial Instruments according to DTR5.3.1R (1) (a)
SUBTOTAL 8. B 1
B 2: Financial Instruments with similar economic effect according to DTR5.3.1R (1) (b)
SUBTOTAL 8.B.2
In case of proxy voting, please identify:
Name of the proxy holder
The number and % of voting rights held
The date until which the voting rights will be held
Additional information xvi
| Place of completion | London, United Kingdom |
| Date of completion | 20 July 2026 |
Notes
Name of ultimate controlling person A (chain 1)
Name of controlled undertaking B
Name of controlled undertaking C
Name of ultimate controlling person A (chain 2)
Name of controlled undertaking B
Name of controlled undertaking D
Name of ultimate controlling person A (chain3)
Name of controlled undertaking E
Name of controlled undertaking F
xvi Example: Correction of a previous notification.
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