WRAP Retail Offer for up to £100,000

Sareum Holdings PLC (AIM: SAR), a clinical-stage biotechnology company developing next-generation kinase inhibitors for autoimmune disease and cancer, is pleased to announce a retail offer via the Winterflood Retail Access Platform (“WRAP”) to raise up to £100,000 (the “Retail Offer”) through the issue of new ordinary shares of 1.25 pence each in the capital of the Company (“Ordinary Shares”). Under the Retail Offer up to 714,285 new Ordinary Shares (the “Retail Offer Shares”) will be made available at a price of £0.14 per share (the “Issue Price”).

In addition to the Retail Offer and as announced earlier today, the Company has announced a subscription of 22,807,143 new Ordinary Shares (the “Subscription Shares” and together with the Retail Offer Shares, the “New Ordinary Shares”) to raise approximately £3.2 million (before expenses) (the “Subscription”) at a price of £0.14 per Subscription Share (the “Subscription Price”). This earlier announcement sets out the reasons for the Subscription and the intended use of proceeds for both the Subscription and the WRAP Retail Offer (together, the “Fundraising”). The issue price of the WRAP Retail Offer Shares is equal to the Subscription Price. The Retail Offer Shares will not carry the warrants attaching to the Subscription Shares.

For the avoidance of doubt, the Retail Offer is not part of the Subscription. Completion of the Retail Offer is conditional, inter alia, upon the completion of the Subscription but completion of the Subscription is not conditional on the completion of the Retail Offer.

The Retail Offer is conditional on the New Ordinary Shares being admitted to trading on the AIM Market (“AIM”) of the London Stock Exchange plc (“Admission”). It is anticipated that Admission will become effective and that dealings in the New Ordinary Shares will commence on AIM at 8.00 a.m. on 29th October 2026.

Expected Timetable in relation to the Retail Offer

WRAP Retail Offer

Therefore, the Company is making the Retail Offer available to eligible investors in the United Kingdom following release of this announcement through certain financial intermediaries.

The Retail Offer is expected to close at 16:30 on 27th October 2026. Eligible retail investors should note that financial intermediaries may have earlier closing times. The result of the Retail Offer is expected to be announced by the Company on or around 28th October 2026.

There is a minimum subscription of £100 per investor under the Retail Offer. The terms and conditions on which investors subscribe will be provided by the relevant financial intermediaries including relevant commission or fee charges.

The Retail Offer is offered in the United Kingdom under an exception from prohibitions on offers to the public pursuant to paragraph 6 of Part 1 of Schedule 1 to The Public Offers and Admissions to Trading Regulations 2024, as an offer conditional on admission of the Retail Offer Shares to trading on AIM, a primary multilateral trading facility. The Retail Offer is not being made into any jurisdiction other than the United Kingdom.

The Company's LEI is 213800PKERN2DY8FFM72.

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