Drawdown of Equity Prepayment Facility

Cambridge, UK, 23 November 2023 - Sareum Holdings plc (AIM: SAR), a biotechnology company developing next generation kinase inhibitors for autoimmune disease and cancer, announces that it has drawn down on the £0.3 million Second Deposit in respect of the Equity Prepayment Facility announced on 3 August 2023.

In accordance with the terms of the Equity Prepayment Facility, the Company will issue 227,892 four year warrants over ordinary shares of 1.25p each exercisable at a price of £0.829337 to Riverfort.

Unless otherwise defined herein, all capitalised terms in this announcement shall have the meanings assigned to them in the Company's announcements of 3 August 2023.