$4m balance sheet improvement with bond conversion

LONDON and NEW YORK, 10 October 2025 - Renalytix plc (LSE: RENX) (OTCQB: RNLXY), a precision medicine diagnostics company, with kidneyintelX.dkd, the only FDA-approved and Medicare reimbursed prognostic test to support early-stage risk assessment in chronic kidney disease, has been notified by a fund advised by Heights Capital Ireland LLC ("Convertible Bond Investor") that approximately $4m of non-amortizing senior convertible bonds ("Convertible Bonds") will be capitalised via the issue to the Convertible Bond Investor of 31,650,034 ordinary shares, at the recent fundraise issue price of 9.5 pence per share ("Conversions Shares").

The conversion of the Convertible Bonds will provide a significant improvement to Renalytix's balance sheet, improving the Company's net asset position by approximately $4m and saving up to $1.4m in accrued interest over the remaining life of the loan. The conversion will also improve the Company's debt to equity ratio.

Application will be made to the London Stock Exchange for admission of the Conversion Shares to trading on AIM ("Admission"). It is expected that Admission of the Conversion Shares will take place at 8.00 a.m. on 15 October 2025 and that dealings in the Conversion Shares on AIM will commence at the same time.

Total Voting Rights

Following Admission, the Company's total issued share capital will be 437,018,680 Ordinary Shares of £0.0025 each in the capital of the Company ("Ordinary Shares"). Each Ordinary Share carries the right to one vote at a general meeting of the Company. The Company does not hold any Ordinary Shares in treasury.

The above figure may be used by shareholders in the Company as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change in their interest in, the share capital of the Company under the Financial Conduct Authority's Disclosure Guidance and Transparency Rules.