Results of AGM on June 16, 2025 – Update Statement

In accordance with Provision 4 of the UK Corporate Governance Code, PureTech ("PureTech" or the "Company") today provides an update in respect of the results of its Annual General Meeting (AGM) held on June 16, 2025. While all resolutions were approved by shareholders, more than 20% of votes were cast against Resolutions 2 and 9, relating to the Directors' Remuneration Report and the re-election of Ms. Mazumdar-Shaw as a Director, respectively.

Building on prior year practice, and consistent with the Company's commitment to maintaining constructive, transparent dialogue with its shareholders, the Company has continued to actively engage with shareholders throughout 2025. Since the 2025 AGM, the Board has taken further steps to understand the views of shareholders. Specifically, the Company wrote to shareholders representing approximately two-thirds of the Company's issued share capital[1] to offer engagement with the Chair of the Board. Following that initial outreach, meetings were held with shareholders representing nearly 50% of issued share capital1 during the month of July. While a range of topics was discussed, shareholders provided feedback encouraging the Company to focus on alignment with UK remuneration principles, while recognizing the challenges associated with operating as a US-based company. Following these engagements, the Remuneration Committee has reviewed the Company's remuneration practices, including the quantum of equity grants for management. Full details of the Remuneration Committee's decisions will be disclosed in the 2025 Annual Report and Accounts, to be published in 2026.

With respect to the re-election of Ms. Mazumdar-Shaw, the Board believes that she contributes significant value to the Company, while acknowledging the scheduling conflict that impacted her attendance at Board meetings in 2024. The Company notes that the scheduling conflict impacting attendance was administrative in nature and is committed to implementing appropriate measures to ensure optimal Director attendance at Board meetings going forward.

The Board would like to thank the shareholders who have engaged with the Company during this process. The Board will continue to engage openly and constructively with shareholders as it continues to develop the Company's approach to governance, remuneration and reporting in the periods ahead.

[1] Based on the issued share capital as of July 25, 2025.