Issue of Equity

December

2025

THIS

ANNOUNCEMENT

CONTAINS

INSIDE

Pensana Plc (LSE: PRE) (the "Company") announces that it has agreed to issue 658,750 new ordinary shares of £0.001 each in the capital of the Company to Quark Financial Limited ("Quark") and 474, 356 new ordinary shares to Riverfort Global Opportunities PCC Ltd ("Riverfort"). The shares to Riverfort will be issued following warrants granted to Riverfort as part of a secured investment agreement concluded in April 2025. The shares to Quark follow the Subscription Agreement concluded on 9 December 2025.

Application will accordingly be made for 1,113,106 new ordinary shares to be admitted to the Official List and to trading on the Main Market of the LSE and Admission is expected to occur on the LSE on or about 08:00 on 24 December 2025. Following

this

issue,

the

Company's

issued

share

capital

consists

of

339,247,689

Ordinary

Shares.

No

shares

are held in treasury. Therefore, the total number of voting rights of the Company is 339,247,689.

the Financial Conduct Authority's Disclosure and Transparency Rules.

a Regulatory Information Service,

this inside information will be considered to be in the

public domain. The

person

responsible for

arranging for

the

release

of this announcement on behalf of the Company is Paul Atherley (Chairman).

For

further

information,

please