AGM Post-Meeting Shareholder Engagement Update

In accordance with Provision 4 of the UK Corporate Governance Code, Oxford Nanopore Technologies plc (LSE: ONT) is providing an update to the statements made on 4 June 2025 in relation to the voting outcome of Resolution 12 at its 2025 Annual General Meeting ("AGM").

Following the AGM, the Company has undertaken an engagement exercise and invited feedback from its major shareholders to understand why certain shareholders were unable to support the resolution. The Board is grateful to those shareholders who engaged with this process.

Feedback received from shareholders has been consistent with the Board's focus on maximising the long-term potential of Oxford Nanopore. As previously announced, the Company continues to refine its strategic planning process to ensure it prioritises and executes on high-priority opportunities that best leverage the unique capabilities of Oxford Nanopore's technology. This will enable the Company to focus resources where it can create the greatest long-term value for stakeholders.

The appointment of Francis Van Parys as Chief Executive Officer brings extensive experience in scaling life-sciences businesses. Francis will lead the next phase of the commercial strategy and will work closely with the Board to deepen and strengthen the broader capability set across the management team to support the next phase of growth and deliver long-term value for all stakeholders.