Ondine Presented Steriwave Data at IPC 2026

Ondine Biomedical Inc. (LON: OBI), a leader in light-activated antimicrobial therapies, announces that its President and Chief Technology Officer, Dr. Nicolas Loebel, was a featured speaker at the Infection Prevention and Control ("IPC") Conference. The event took place 28-29 April at The National Conference Centre in Birmingham and brought together leading clinicians, infection prevention specialists, and NHS decision-makers from across the UK.

The IPC Conference 2026 featured sessions addressing strategies to reduce healthcare-associated infections ("HAIs"), improve antimicrobial stewardship, and address operational pressures within the NHS. The program included expert-led sessions on surveillance and early identification of infection risks, practical containment strategies, and scalable interventions to improve patient safety while reducing costs. The conference also highlighted the urgent need for innovation-driven solutions to address increasing surgical backlogs, workforce constraints, and the growing burden of antimicrobial resistance ("AMR").

In alignment with the conference's focus on evidence-based best practices and innovation adoption, Ondine Biomedical presented clinical outcomes associated with its Steriwave® nasal photodisinfection, which NHS Supply Chain recently classified as an Innovation Product. This classification reflects Steriwave's alignment with long-term NHS priorities, including reducing AMR, supporting infection prevention, and improving the efficiency and sustainability of healthcare delivery.

• Loebel's presentation, titled "Nasal Photodisinfection: Addressing the Hidden Costs of HAIs", focused on the clinical and economic burden of healthcare-associated infections and the role of nasal decolonisation in reducing infection risk. The presentation highlighted limitations of traditional approaches and outlined how Steriwave nasal photodisinfection offers a compelling non-antibiotic alternative aligned with evolving antimicrobial stewardship priorities.

Key highlights from the presentation included:

• Burden of HAIs: Healthcare-associated infections drive significant clinical and economic impact, including increased length of stay, higher treatment costs, and reduced surgical capacity. With an average of 9.7 additional hospital days per major SSI, each infection can displace two to three subsequent surgical procedures.
• Limitations of antibiotic decolonisation: The presentation outlined challenges associated with antibiotic-based nasal decolonisation, including resistance development, multi-day treatment protocols, and disruption of the nasal microbiome.
• Photodisinfection mechanism and profile: Steriwave nasal photodisinfection was presented as a rapid, single-dose, broad-spectrum antimicrobial approach designed to eliminate nasal pathogens without contributing to antimicrobial resistance. The nurse-led application supports consistent, high compliance.
• Clinical and real-world data: Data from Steriwave use across multiple clinical and real-world settings in Canada and the UK were presented, including reductions in surgical site infections and ICU-acquired pneumonia. These findings were associated with shorter lengths of stay, faster recovery, and improved patient flow, supporting hospitals in reclaiming bed capacity and increasing procedural throughput.
• Health economic impact: Health economic analysis of Steriwave was highlighted, demonstrating substantial reductions in infection-related costs and improved hospital efficiency, supporting more sustainable NHS operations.
• Nicolas Loebel remarked:

"Hospital-acquired infections are not only a clinical challenge but also place a significant logistical and financial burden on healthcare systems. Our nasal photodisinfection helps clinicians to proactively protect patients while improving efficiency and capacity within their facilities in an era of rising antimicrobial resistance."

Carolyn Cross, Ondine's CEO added:

"Ondine's participation in IPC 2026 reflects the growing interest we are seeing in the UK market and engagement with NHS institutions around non-antibiotic approaches to infection prevention. Steriwave's recent classification as an Innovation Product by NHS Supply Chain further reinforces this momentum and its alignment with NHS priorities, including improving patient outcomes while managing costs."

The two-step process involves applying the Steriwave formulation in the nostrils where it electrostatically binds to microbes rather than human cells. The area is then illuminated with safe red light to activate the formulation, triggering an oxidative burst that physically destroys all manner of pathogens within minutes. This rapid and overwhelming oxidative stress makes it extremely difficult for pathogens to develop resistance, and the process stops immediately once the light is turned off. Steriwave has been used in a growing number of hospitals since 2011.

About Ondine Biomedical Inc.