Appointment of Non-Executive Director

Seasoned life sciences executive with extensive Board and financial expertise

hVIVO plc (AIM: HVO), a full-service early phase Contract Research Organisation (CRO) and the world leader in human challenge clinical trials, announces the appointment of Richard Cotton as Independent Non-Executive Director, effective today. Richard will also serve as Chair of the Audit Committee and as a member of the Remuneration and Nominations Committees.

Richard brings extensive Board-level and financial expertise, including experience serving as Chair, Audit Chair and Senior Independent Director, as well as holding advisory and senior financial leadership roles across the life sciences and other sectors.

Richard currently serves as Audit Chair and Lead Independent Director at Nasdaq-listed AI predictive diagnostics company Spectral AI and is Senior Independent Director and Audit Committee Chair at AIM-listed topical oxygen wound therapy company AOTI. He is also Financial Adviser at Novumgen, a privately owned Specialty Pharmaceuticals company, and NED at Sherwood Forest Hospitals NHS Foundation Trust.

His prior executive roles include highly successful tenures as CFO at FTSE150 animal health company Dechra Pharmaceuticals plc, and as CFO at medical device and drug formulation business Consort Medical plc. A Fellow of the Chartered Institute of Management Accountants, Mr Cotton holds a BA (Hons) in Business Studies from Kingston University.

Shaun Chilton, Non-Executive Chair of hVIVO plc, said: "We welcome Richard to the Board of hVIVO. His extensive financial, operational and governance expertise, combined with his life sciences experience will significantly enhance the Board's capabilities as we focus on the strategic opportunities open to the Company and delivering long-term shareholder value."

Richard Cotton, Incoming Non-Executive Director of hVIVO plc, said: "I am excited to be able to contribute my experience and expertise to support hVIVO's growth. The Company is at an exciting phase with the foundation of a global leading position in human challenge trials with an increasingly diversified service offering, a robust pipeline and strong fundamentals. I look forward to working closely with the Board and leadership team."

Additional Information on the Board Appointment

The following additional information is provided with regards to the appointment of Richard John Cotton, aged 64, in accordance with Rule 17 and Schedule 2(g) of the AIM Rules for Companies:

Sherwood Forest NHS Foundation Trust

Spectral AI Inc

Spectral IP Inc

Spectral MD UK Limited

On 24 June 2005, Mr Cotton was appointed as director of Wagon Services Limited and subsequently resigned as a director on 31 October 2008. Wagon Services Limited entered administration on 8 December 2008 as a result of a downturn in trading caused by the global economic conditions at that time and was subsequently dissolved on 28 February 2010.

Mr Cotton was a director of a number of former dormant subsidiaries of McLeod Russel plc which were liquidated as part of a corporate reorganisation following its acquisition by SPX Corp. The companies were dissolved by creditors voluntary liquidation on the dates shown below:

Mr Cotton does not hold any shares or options in the Company.

Anthony Farrell, Niall Gilchrist