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Avacta completes sale of Coris Bioconcept

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Avacta completes sale of Coris Bioconcept to 3B BlackBio Dx Ltd.

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LONDON AND PHILADELPHIA - September 1, 2025 - Further to the announcement on July 28, 2025, Avacta Group plc (AIM: AVCT) a life sciences company developing innovative, targeted oncology drugs, today announces that all closing conditions to the sale of the entire issued share capital of Coris Bioconcept SRL to 3B BlackBio Dx Ltd have been satisfied and the completion of the sale took place on Friday August 29, 2025.

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The preCISION® platform comprises an anticancer payload conjugated to a proprietary peptide that is a highly specific substrate for fibroblast activation protein (FAP) which is upregulated in most solid tumors compared with healthy tissues. The preCISION® platform harnesses this tumor specific protease to cleave preCISION® peptide drug conjugates and preCISION® antibody/Affimer® drug conjugates in the tumor microenvironment, thus releasing active payload in the tumor and reducing systemic exposure and toxicity, allowing dosing to be optimized to deliver the best outcomes for patients.

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