| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Ian Cloke |
| 2. | Reason for the notification |
| a. | Position/status | Chief Operating Officer |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Sale of Shares |
| c. | Price(s) and volume(s) | .833 |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 61.35 pence sold 82,833 £20,143.05 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Ian Cloke |
| 2. | Reason for the notification |
| a. | Position/status | Chief Operating Officer |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Purchase of Ordinary shares into ISA account |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 61.45 pence purchased 32,043 £19,690.42 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Elizabeth Bingham |
| 2. | Reason for the notification |
| a. | Position/status | Person closely associated with Ian Cloke, Chief Operating Officer of the Company |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Sale of Ordinary shares |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 61.12 pence sold 32,000 £19,589.18 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Elizabeth Bingham |
| 2. | Reason for the notification |
| a. | Position/status | Person closely associated with Ian Cloke, Chief Operating Officer of the Company |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Purchase of Ordinary shares into ISA account |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 61.18 pence purchased 31,028 £19,190.51 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Anastasia Deulina |
| 2. | Reason for the notification |
| a. | Position/status | Chief Financial Officer |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Sale of Ordinary Shares |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 59.49 pence sold 100,000 £59,492.86 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Anastasia Deulina |
| 2. | Reason for the notification |
| a. | Position/status | Chief Financial Officer |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Purchase of Ordinary Shares |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 60.30 pence purchased 75,853 £45,743.00 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Peter Brooker |
| 2. | Reason for the notification |
| a. | Position/status | Person closely associated with Anastasia Deulina, Chief Financial Officer of the Company |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Purchase of Ordinary Shares into ISA account |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 60.93 pence purchased 53,669 £32,699.61 |
| f. | Place of the transaction | XLON |
| 1. | Details of the person discharging managerial responsibilities / person closely associated |
| a. | Name | Gavin Wilson |
| 2. | Reason for the notification |
| a. | Position/status | Non Executive Director |
| b. | Initial notification/Amendment | Initial Notification |
| a. | Name | Afentra plc |
| b. | LEI | 21380028BFDFJK8BRX92 |
| a. | Description of the Financial instrument, type of instrument Identification code | Ordinary shares of £0.10 per share par value GB00B4X3Q493 |
| b. | Nature of the transaction | Purchase of Ordinary Shares |
| c. | Price(s) and volume(s) | |
| d. | Aggregated information · Aggregated volume · Price | Price Volume Total 61.00 pence purchased 35,000 £21,350 |
| f. | Place of the transaction | London Stock Exchange AIMX |